GMFB Antibody
Rabbit Polyclonal
Catalog number: 10690-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | mouse brain tissue, human brain tissue, human heart tissue, mouse heart tissue |
| Positive IHC detected in | human colon cancer |
| Recommended dilution | WB: 1:1000-1:10000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with 10690-1-AP(GMFB Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human colon cancer using 10690-1-AP(GMFB Antibody) at Dilution 1:100 (under 25x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | GMFB fusion protein ag1104 | Full name | glia maturation factor, beta |
|
Calculated molecular weight |
17kd |
Observed molecular
weight |
17kd |
|
GenBank accession number |
BC005359 | Gene ID (NCBI) | 2764 |
| Gene symbol | GMFB | Synonyms | GMF |
Background
GMFB, Glia maturation factor beta, is a nerve growth factor implicated in nervous system development. It was reported that GMF-beta promotes the phenotypic expression of glia and neurons and inhibits the proliferation of their respective tumors in culture cells. GMF-beta protein is specific to the brain where it is expressed in glial cells (mainly astrocytes) and insome neurons. Higher levels of GMFB were found in the central nervous system, except for the spinal cord, and in thymus and colon. |
