KRT19 Antibody
Rabbit Polyclonal
Catalog number: 10712-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IF, IHC, WB |
| Species specificity | human, mouse; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | A431 cells, A549 cells, HepG2 cells, MCF7 cells, mouse brain tissue, mouse placenta tissue |
| Positive IHC detected in | human prostate cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
A431 cells were subjected to SDS PAGE followed by western blot with 10712-1-AP(KRT19 Antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded human prostate cancer using 10712-1-AP(KRT19 Antibody) at Dilution 1:100 (under 25x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | KRT19 fusion protein ag1085 | Full name | keratin 19 |
|
Calculated molecular weight |
40kd |
Observed molecular
weight |
44-50 kDa |
|
GenBank accession number |
BC007628 | Gene ID (NCBI) | 3880 |
| Gene symbol | KRT19 | Synonyms | CK19; K19; K1CS; MGC15366 |
Background
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells. Keratin expression is highly regulated, tissue specific, and varies according to cell-state. Type I keratins consist of acidic, low molecular weight proteins with MW ranging from 40 kDa (KRT19) to 64 kDa (KRT9). Type 2 keratins consist of basic or neutral, high molecular weight proteins with MW from 52 kDa (KRT8) to 67 kDa (KRT18). Keratin 19 is a type I cytokeratin. It is a biochemical marker of skin stem cells in vivo and in vitro. |
