RBM3 Antibody
Rabbit Polyclonal
Catalog number: 14363-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | mouse, rat |
| Positive WB detected in | HeLa cells, A375 cells, HepG2 cells, MCF7 cells, Raji cells |
| Positive IHC detected in | human testis |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
HeLa cells were subjected to SDS PAGE followed by western blot with 14363-1-AP(RBM3 Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human testis using 14363-1-AP(RBM3 Antibody) at Dilution 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human testis using 14363-1-AP(RBM3 Antibody) at Dilution 1:50 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | RBM3 fusion protein ag5934 | Full name | RNA binding motif (RNP1, RRM) protein 3 |
|
Calculated molecular weight |
17kd |
Observed molecular
weight |
17-20kd |
|
GenBank accession number |
BC006825 | Gene ID (NCBI) | 5935 |
| Gene symbol | RBM3 | Synonyms | IS1-RNPL; RNPL |
Background
RBM3, also named as RNPL, is a cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. It reduces the relative abundance of microRNAs, when overexpressed. RBM3 enhances phosphoryaltion of translation initiation factors and active polysome formation. It is up-regulated in human tumors. RBM3 is a potential proto-oncogenic proteins upon overexpression. (PMID: 19900510 ) This antibody can bind the close sequences genes. |
