TNFAIP8L2 Antibody
Rabbit Polyclonal
Catalog number: 15940-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IF, IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, mouse, rat |
| Positive WB detected in | mouse cerebellum tissue, HL-60 cells, mouse small intestine tissue, rat lymph tissue |
| Positive IHC detected in | human lymphoma |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 15940-1-AP(TNFAIP8L2 Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human lymphoma using 15940-1-AP(TNFAIP8L2 Antibody) at Dilution 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human lymphoma using 15940-1-AP(TNFAIP8L2 Antibody) at Dilution 1:50 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | TNFAIP8L2 fusion protein ag7964 | Full name | tumor necrosis factor, alpha-induced protein 8-like 2 |
|
Calculated molecular weight |
184aa,21kd |
Observed molecular
weight |
18kd |
|
GenBank accession number |
BC063014 | Gene ID (NCBI) | 79626 |
| Gene symbol | TNFAIP8L2 | Synonyms | FLJ23467; TIPE2 |
Background
TIPE2 (TNF-α-inducible protein 8-like 2, or TNFAIP8L2), a newly identified protein, is essential for maintaining immune homeostasis. TIPE2 shares considerable sequence homology with members of the tumor necrosis factor-α-inducible protein 8 (TNFAIP8) family, which are thought to regulate cellular and immune homeostasis. TIPE2 acts as a negative regulator of Toll-like receptor and T-cell receptor function and is preferentially expressed in lymphoid tissues. TIPE2 plays an essential role for a signal transduction pathway that links inflammatory immune response to specific conditions after cerebral ischemia |
