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  • Home
  • p53 signaling pathway
Activation Inhibition Translocation Phosphorylation Ubiquitin Ub P Apoptosis Nitric Oxide Hypoxia Heat/cold shock DNA damage Cell Cycle Arrest G1 Arrest G2 Arrest DNA Repair Inhibition of IGF-1/mTOR Pathway Apoptosome Proteasome Gene Transcription ATM ATR P53 CHEK1 CHEK2 DNA-PKcs JNK p38 CDK1 RB RB E2F E2F CDK2 CDK4/6 p21,CIP1 Caspase 9 Caspase 3 BAD PUMA Noxa MDM2 Cyclin D Cyclin B GADD45A GADD45A Sestrin 2 14-3-3σ Cyclin E PTEN TSC2 Bcl-XL BCL2 BAX BAK Cyto c P P P P P P P P

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