AK2 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66127-1-Ig |CloneNo.: 3H2C10

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Con: 270 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HeLa cells, HEK-293 cells

Positive IHC detected in:
human liver tissue, human heart tissue, human liver tissue

Positive IF detected in:
HepG2 cells, HeLa cells

Positive FC detected in:
HepG2 cells

Recommended dilution:
WB : 1:1000-1:8000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
adenylate kinase 2

Calculated molecular weight:
26 kDa

Observed molecular weight:
29 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AK2

Synonyms
adenylate kinase 2, ADK2, AK 2, AK2, ATP AMP transphosphorylase 2
Background

AK2(Adenylate kinase 2, mitochondrial ) is also named as ADK2 and belongs to the adenylate kinase family. It plays a unique role in energy metabolism and energy transfer by regulating the ATP/ADP rate between the cytoplasma matrix and the mitochondria and it is increased expression during adipocyte and B cell differentiation(PMID:23020757). AK2 catalyzes the reversible transfer of a phosphoryl group from ATP to AMP(PMID:19043417). Defects in AK2 are the cause of reticular dysgenesis (RDYS)(PMID:19043416). It has 6 isoforms produced by alternative splicing.


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