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HumanKine® Human Cell-expressed Proteins

HumanKine® recombinant proteins are created in HEK293 cells using animal-free components.

  • High bioactivity & stability

  • Lot-to-lot consistency 

  • Native human conformation & post-translational modifications

  • Endotoxin-free, xeno-free & tag-free

All HumanKine® recombinant proteins are produced in Proteintech’s in-house GMP grade laboratory adhering to strict quality control regulations. Find out more here

Browse all HumanKine® recombinant proteins, including Cytokines and Growth Factors
See the full list of HumanKine® Cytokines and Growth Factors
Benefits of HumanKine® recombinant proteins

Recombinant proteins are proteins encoded by a gene - recombinant DNA - that has previously been cloned in a system that supports the gene expression and translation of messenger RNA.

Proteins coexpressed in bacteria will not possess post-translational modifications, e.g., phosphorylation or glycosylation. For activity, many proteins require glycosylation and processing only available in eukaryotic systems. Human stem cell technology and CAR-T cell therapy also require culture media whose components must be animal component and xenobiotic free.

HumanKine® recombinant proteins are created in HEK293 cells using animal-free components. Our human expression system ensures that proteins have native conformation and post-translational modifications to optimize biological activity. No expression tags, xeno-free…just high quality proteins.

HumanKine® Human Cell-expressed Protein Whitepapers
Time-Saving Dendritic Cell Generation No Medium Change - Less Reagents With HumanKine® GM-CSF and HumanKine IL4 Native Glycosylation Is Important For Biological Function and Activity of Recombinant Human Proteins
HumanKine® IL-23 100x More Potent For Induction of Human Th17 Cells HumanKine® IL-17 Effective Tool for Autoimmune Disease Research
Effective Polarization of Human Th17 Cells with Biologically Relevant HumanKine® TGFβ1, TGFβ2, and TGFβ3 Expressed in Human Cells Effective Differentiation of Th17 Cells With HumanKine® Cytokines Expressed in Human Cells
Efficient Induction of Th17 Cells with HumanKine® TGFβ1 HumanKine® Noggin Human Cell-expressed Glycosylated Disulfide-linked Homodimer

See below for a full list of HumanKine® products:
Product Name Catalog number Activity spec. Purity Citations
Activin A HZ-1138 ≤5 ng/mL EC50 >95% 16
beta NGF HZ-1222 ≤3 ng/mL EC50 >95%  
BMP-2 HZ-1128 ≤60 ng/mL EC50 >95% 21
BMP-4 HZ-1045 ≤10 ng/mL EC50 >95% 41
BMP-7 HZ-1229 ≤100 ng/mL EC50 >95% 6
Cystatin C HZ-1211 ≤5 µM IC50 >95%  
EPO HZ-1168 ≤2.5 ng/mL EC50 >95% 3
FGF Basic TS HZ-1285 ≤0.5 ng.mL EC50 >95% 8
FGF-4 HZ-1218 ≤1.25 ng/mL EC50 >95%  
FGF-7 (KGF) HZ-1100 ≤7.5 ng/mL EC50 >95% 1
FGF-8b HZ-1103 ≤10 ng/mL EC50 >95% 1
FLT3 Ligand HZ-1151 ≤0.8 ng/mL EC50 >95% 10
G-CSF HZ-1207 ≤0.1 ng/mL EC50 >95% 6
GDNF HZ-1311 ≤ 10 ng/mL  EC50 >95%  
GM-CSF HZ-1002 ≤0.5 ng/mL EC50 >95% 10
HGF HZ-1084 ≤20 ng/mL EC50 >95% 8
HGH HZ-1007 ≤0.5 ng/mL EC50 >95% 2
HSA HZ-3001 N/A >95%  
IFN alpha 2A HZ-1066 ≤0.4 ng/mL EC50 >95% 4
IFN alpha 2B HZ-1072 ≤0.12 ng/mL EC50 >95% 2
IFN beta HZ-1298 ≤0.1 ng/mL EC50 >95%  
IFN gamma HZ-1301 ≤0.05 ng/mL EC50 >95% 3
IL-1 beta HZ-1164 ≤0.05 ng/mL EC50 >95% 16
IL-2 HZ-1015 ≤5 ng/mL EC50 >95% 5
IL-3 HZ-1074 ≤2 ng/mL EC50 >95% 10
IL-4 HZ-1004 ≤0.6 ng/mL EC50 >95% 17
IL-6 HZ-1019 ≤0.5 ng/mL EC50 >95% 19
IL-7 HZ-1281 ≤1 ng/mL EC50 >95%  
IL-9 HZ-1240 ≤1 ng/mL EC50 >95% 2
IL-10 HZ-1145 ≤1.5 ng/mL EC50 >95%  
IL-12 HZ-1256 ≤2 ng/mL EC50 >95% 3
IL-17 (IL-17A) HZ-1113 ≤2 ng/mL EC50 >95% 3
IL-17F HZ-1116 ≤10 ng/mL EC50 >95%  
IL-23 HZ-1254 ≤4 ng/mL EC50 >95% 11
IL-27 HZ-1275 ≤12 ng/mL EC50 >95% 1
IL-28A HZ-1235 ≤5 ng/mL EC50 >95% 2
IL-28B HZ-1245 ≤1 ng/mL EC50 >95%
IL-29 HZ-1156 ≤5 ng/mL EC50 >95% 2
Lefty-1 HZ-1109 ≤40 ng/mL EC50 >95% 1
LIF HZ-1292 ≤0.2 ng/mL EC50 >95%  
M-CSF HZ-1192 ≤4 ng/mL EC50 >95% 5
Noggin HZ-1118 ≤15 ng/mL EC50 >95% 5
Oncostatin M HZ-1030 ≤1 ng/mL EC50 >95%
3
PDGF-aa HZ-1215 ≤10 ng/mL EC50 >95%  
PDGFbb HZ-1308  ≤3 ng/mL EC50 >95% 1
Pleiotrophin-PTN HZ-1278 N/A >95%  
pro-IGF-II HZ-1161 ≤50 ng/mL EC50 >95% 1
SCF HZ-1024 ≤25 ng/mL EC50 >95% 9
Sonic Hedgehog (SHH) HZ-1306 ≤350 ng/mL EC50 >90%
 
TGF beta 1 HZ-1011 ≤0.5 ng/mL EC50 >95% 82
TGF beta 2 HZ-1092 ≤0.5 ng/mL EC50 >95%  4
TGF beta 3 HZ-1090 ≤0.5 ng/mL EC50 >95% 8
Thrombin HZ-3010 N/A >95% 1
TNF alpha HZ-1014 ≤0.5 ng/mL EC50 >95%  9
TPO HZ-1248 ≤5 ng/mL EC50 >95% 2
VEGF 121 HZ-1204 ≤15 ng/mL EC50 >95%  14
VEGF 165 HZ-1038 ≤5 ng/mL EC50 >95%  11
Wnt3A HZ-1296 ≤20 ng/mL EC50 >90%  1

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