Caspase 7 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 10459-1-AP

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Con: 0 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
caspase 7, apoptosis-related cysteine peptidase

Calculated molecular weight:
390aa,51 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CASP7

Synonyms
CASP7, Caspase7, MCH3, Apoptotic protease Mch 3, CASP 7
Background

Caspase 7(CASP7), like caspases 3 and 6, contains a short prodomain and, upon apoptotic induction, the 35 kDa proform is converted into a 32 kDa intermediate or preactive form which is further processed into two active subunits consisting of the p20 or large (18 kDa) subunit and the p10 or small (11 kDa) subunit and it is present in the brain, which is up-regulated and activated after traumatic injury(PMID:15953353). Caspase-7 is classified as a member of the subgroup of cysteine proteases most related to the Caenorhabditis elegans factor CED-3, which also includes caspase-3, -6, and -9(PMID:9426061). The protein is involved in the activation cascade of caspases responsible for apoptosis execution. This antibody is specific to CASP7.


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