Caspase 9/p35/p10 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 23821-1-AP

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Con: 73 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
HeLa cells, HeLa cells

Positive IHC detected in:
human pancreas tissue, human heart tissue, human pancreas tissue

Positive IF detected in:
HUVEC cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
caspase 9, apoptosis-related cysteine peptidase

Calculated molecular weight:
46 kDa

Observed molecular weight:
46 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CASP9

Synonyms
Background

Caspase 9, apoptosis-related cysteine protease (CASP9,synonyms: MCH6, APAF3, APAF-3, ICE-LAP6, CASPASE-9c)is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. CASP9 is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade


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