p57KIP2-Specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 19804-1-AP

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Freight/Packing

Con: 24 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
cyclin-dependent kinase inhibitor 1C (p57, Kip2)

Calculated molecular weight:
32 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CDKN1C

Synonyms
BWCR, BWS, CDKN1C, KIP2, p57, p57Kip2, WBS
Background

CDKN1C, also named as p57KIP2 and KIP2, belongs to the CDI family. CDKN1C is a potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. It is a negative regulator of cell proliferation. CDKN1C may play a role in maintenance of the non-proliferative state throughout life. The antibody is specific to CDKN1C.


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