CFP Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17192-1-AP

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Freight/Packing

Con: 35 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Jurkat cells

Positive IHC detected in:
human spleen tissue

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
complement factor properdin

Calculated molecular weight:
469aa,51 kDa

Observed molecular weight:
50 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CFP

Synonyms
BFD, CFP, Complement factor P, complement factor properdin, PFC, PFD, PROPERDIN
Background

CFP, also named as Properdin or CFP, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105).


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