DAD1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 10531-1-AP

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Freight/Packing

Con: 95 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HepG2 cells

Positive IHC detected in:
human liver cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
defender against cell death 1

Calculated molecular weight:
12 kDa

Observed molecular weight:
16-20 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DAD1

Synonyms
DAD 1, DAD1, defender against cell death 1, OST2
Background

DAD1 (defender against cell death 1) is a downstream target of the NFkB survival pathway and exhibits an antiapoptotic function. It is also named as OST2 (Oligosaccharyl transferase2) and catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Increased expression of DAD1 has been observed in various tumors.


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