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DEDD Polyclonal antibody

DEDD Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 10816-1-AP

Synonyms

CASP8IP1, DEDD, DEDD1, DEDPro1, DEFT, FLDED 1, FLDED1, KE05

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human prostate cancer tissue using DEDD Polyclonal antibody (10816-1-AP)

    IHC staining of human prostate cancer using 10816-1-AP

    Immunohistochemical analysis of paraffin-embedded human prostate cancer using 10816-1-AP (DEDD antibody) at dilution of 1:50 (under 10x lens).

Tested Applications

Positive IHC detected inhuman prostate cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

IHCSee 1 publications below

Product Information

10816-1-AP targets DEDD in IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen DEDD fusion protein Ag1195
Full Name death effector domain containing
Calculated Molecular Weight 37 kDa
GenBank Accession NumberBC013910
Gene Symbol DEDD
Gene ID (NCBI) 9191
RRIDAB_2091534
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

DEDD, a member of a family of death effector domain-containing proteins, plays crucial roles in mediating apoptosis, regulating cell cycle, and inhibiting cell mitosis. DEDD may be a novel tumor repressor, which impedes metastasis by reversing the epithelial-mesenchymal transition (EMT) process in breast and colon cancers (PMID: 24839027).

Protocols

Product Specific Protocols
IHC protocol for DEDD antibody 10816-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

Methods Mol Biol

Use of the Tumor Repressor DEDD as a Prognostic Marker of Cancer Metastasis.

Authors - Qi Lv
View Article