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- KD/KO Validated
RIPK5 Polyclonal antibody
RIPK5 Polyclonal Antibody for WB, IF, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat and More (1)
Applications
WB, IF, IHC, ELISA
Conjugate
Unconjugated
Cat no : 20102-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | mouse brain tissue, rat liver tissue |
Positive IF detected in | HepG2 cells |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:500-1:1000 |
Immunofluorescence (IF) | IF : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Published Applications
KD/KO | See 1 publications below |
WB | See 1 publications below |
IHC | See 1 publications below |
IF | See 1 publications below |
Product Information
The immunogen of 20102-1-AP is RIPK5 Fusion Protein expressed in E. coli.
Tested Reactivity | human, mouse, rat |
Cited Reactivity | human, mouse, monkey |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | RIPK5 fusion protein Ag13678 |
Full Name | dual serine/threonine and tyrosine protein kinase |
Calculated Molecular Weight | 66 kDa, 105 kDa |
GenBank Accession Number | BC060870 |
Gene Symbol | DSTYK |
Gene ID (NCBI) | 25778 |
RRID | AB_10694146 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Protein-serine/threonine and protein-tyrosine kinases (PSK and PTK) comprise two major classes of protein kinases. They provide a key switch dictating the dynamic nature and graded regulation of signal transduction pathway activities in cellular organization. DSTYK is a members of the RIP serine/threonine kinase family which involved in activation of NF-KB, JNK, and p38, and induction of apoptosis. This antibody is specific to DSTYK.
Protocols
Product Specific Protocols | |
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WB protocol for RIPK5 antibody 20102-1-AP | Download protocol |
IF protocol for RIPK5 antibody 20102-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Nat Commun Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway. | ||
Cell Death Dis Loss of DSTYK activates Wnt/β-catenin signaling and glycolysis in lung adenocarcinoma
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