Factor XIIIa Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17223-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse lung tissue

Recommended dilution:
WB : 1:200-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
coagulation factor XIII, A1 polypeptide

Calculated molecular weight:
732aa,83 kDa

Observed molecular weight:
80-85 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
F13A1

Synonyms
Coagulation factor XIIIa, F13A, F13A1, Transglutaminase A chain
Background

Factor XIIIa is a blood proenzyme that catalyzes intermolecular cross-linking of fibrinogen and is involved in clotting cascade. It has been identified in various tissues including placenta, uterus, and prostate. Anti- Factor XIIIa has been found to be useful in differentiating between dermatofibroma (90% positive) and desmoplastic malignant melanoma (negative). Factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor , and meningioma.


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