F7 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 23058-1-AP

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Freight/Packing

Con: 61 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
human placenta tissue, human plasma tissue, mouse liver tissue

Positive IF detected in:
HUVEC cells

Recommended dilution:
WB : 1:200-1:1000
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen Affinity purified

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
coagulation factor VII (serum prothrombin conversion accelerator)

Calculated molecular weight:
466aa,52 kDa

Observed molecular weight:
49-55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
F7

Synonyms
Coagulation factor VII, Eptacog alfa, F7, Proconvertin, SPCA
Background

F7(Coagulation factor VII) is also named as serum prothrombin conversion accelerator(SPCA). It is the key triggering enzyme of the extrinsic coagulation pathway. Hepatocytes are the predominant source of F7 production under normal physiologic conditions, although F7 is also expressed by monocytes/macrophages in inflammation and atherosclerosis(PMID:17018600). This protein has 2 isoforms produced by alternative splicing.


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