Frizzled 10 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 18175-1-AP

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Con: 45 μg/150 μl

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Species specificity:
human, mouse, rat, zebrafish

Positive WB detected in:
mouse kidney tissue, HeLa cells

Positive IHC detected in:
human kidney tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
frizzled homolog 10 (Drosophila)

Calculated molecular weight:
581aa,65 kDa

Observed molecular weight:
65 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FZD10

Synonyms
CD350, Frizzled 10, FZ 10, FZD10, FzE7, hFz10
Background

FZD10 (Frizzled homolog 10) is a member of the frizzled gene family, and considered as a seven-transmembrane Wnt-signaling receptor. FZD10 is expressed at high levels on the cell surface of almost all synovial sarcoma tissues but absent in most normal organs except for placenta. Up-regulation of FZD10 mRNA in several types of human cells might lead to carcinogenesis through activation of the beta-catenin-TCF signaling pathway with some class of WNTs.


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