HNF1A Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22426-1-AP

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Freight/Packing

Con: 84 μg/150 μl

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Species specificity:
human, rat, mouse

Positive WB detected in:
rat liver tissue, SMMC-7721 cells

Positive IP detected in:
mouse liver tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen Affinity purified

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
HNF1 homeobox A

Calculated molecular weight:
631aa,67 kDa

Observed molecular weight:
67 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
HNF1A

Synonyms
HNF 1 alpha, HNF 1A, HNF1, HNF1 homeobox A, HNF1A, LFB1, MODY3, TCF 1, TCF1, Transcription factor 1
Background

HNF-1 , a homoeprotein family designated the Hepatocyte Nuclear Factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. HNF1 as a transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. It is required for the expression of several liver specific genes and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.


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