ING2-specific Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 16186-1-AP

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Freight/Packing

Con: 37 μg/150 μl

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Tested Applications

Applications:
ELISA, WB, IF
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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
inhibitor of growth family, member 2

Calculated molecular weight:
33 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ING2

Synonyms
ING2, p33ING2, p32, ING1Lp, ING1L
Background

ING2, also named as ING1L, belongs to the ING family and contains a PHD-type zinc finger. It is induced by the DNA-damaging agents etoposide and neocarzinostatin. As a candidate tumor suppressor, ING2 seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. It is a component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. Recent finding reported that ING2 regulates muscle differentiation by regulating chormatin remodeling program. Catalog#16186-1-AP is rabbit polyclonal antibdoy raised against specific ING2 polypeptides and detects p33ING2 but not other INGs.


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