NRAS-Specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18296-1-AP

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 48 μg/150 μl

Choose size:

Please visit your regions distributor:

Tested Applications

Applications:
ELISA
Application not tested? Please see our Guarantee




Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
neuroblastoma RAS viral (v-ras) oncogene homolog

Calculated molecular weight:
21 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NRAS

Synonyms
ALPS4, GTPase NRas, HRAS1, N ras, NRAS, NRAS1, Transforming protein N Ras
Background

NRAS, also named as N-ras and NRAS1, is neuroblastoma RAS viral (v-ras) oncogene homolog from the mammalian ras gene family and it is a member of the small GTPase superfamily. RAS proteins are involved in signal transduction pathways, and bind GDP/GTP and possess intrinsic GTPase activity. It is mapped on chromosome 1, and it is activated in HL60, a promyelocytic leukemia line. Defects in NRAS are a cause of juvenile myelomonocytic leukemia (JMML). The antibody is specific to NRAS, can’t recognize HRAS and KRAS.


Back
to top