SSBP1 Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 12212-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 21 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A375 cells, mouse pancreas tissue, rat pancreas tissue

Positive IF detected in:
A375 cells

Recommended dilution:
WB : 1:500-1:1000
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
single-stranded DNA binding protein 1

Calculated molecular weight:
148aa,17 kDa

Observed molecular weight:
17 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SSBP1

Synonyms
Mt SSB, MtSSB, PWP1 interacting protein 17, SSBP, SSBP1
Background

SSBP1 is a housekeeping gene involved in mitochondrial biogenesis. it binds preferentially and cooperatively to ss-DNA in the maintainance of genome stability. SSBP1 acted as a homotetramer to stabilize the displaced single strand of the normal and expanded displacement loop (D loop) during mtDNA replication, thus preventing formation of secondary single-stranded DNA structures, which could stop the gamma-DNA polymerase


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