ST7L Polyclonal antibody
ST7L Polyclonal Antibody for WB, IP, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
mouse, human
Applications
WB, IP, CoIP, ELISA
Conjugate
Unconjugated
Cat no : 17567-1-AP
Synonyms
Validation Data Gallery
Tested Applications
| Positive WB detected in | L02 cells, MCF-7 cells, T-47D cells |
| Positive IP detected in | mouse testis tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 3 publications below |
| CoIP | See 1 publications below |
Product Information
17567-1-AP targets ST7L in WB, IP, CoIP, ELISA applications and shows reactivity with mouse, human samples.
| Tested Reactivity | mouse, human |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | ST7L fusion protein Ag11768 |
| Full Name | suppression of tumorigenicity 7 like |
| Calculated Molecular Weight | 575 aa, 65 kDa |
| Observed Molecular Weight | 60-70 kDa |
| GenBank Accession Number | BC065501 |
| Gene Symbol | ST7L |
| Gene ID (NCBI) | 54879 |
| RRID | AB_2194882 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
ST7 (suppressor of tumorigenicity 7) gene has been proposed to be a tumor suppressor gene, product of which is a multi-pass membrane protein belonging to the ST7 family. ST7L (suppressor of tumorigenicity 7 protein-like) gene encodes a multi-pass membrane protein also belonging to the ST7 family, 8 isoforms produced by alternative splicing have been described . However, the molecular function of this gene product has not been determined so far.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for ST7L antibody 17567-1-AP | Download protocol |
| IP protocol for ST7L antibody 17567-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Cell Death Dis MicroRNA-23b functions as an oncogene and activates AKT/GSK3β/β-catenin signaling by targeting ST7L in hepatocellular carcinoma. | ||
J Exp Clin Cancer Res Long noncoding RNA MIR31HG inhibits hepatocellular carcinoma proliferation and metastasis by sponging microRNA-575 to modulate ST7L expression. | ||
Int J Mol Med miR-378 functions as an onco-miRNA by targeting the ST7L/Wnt/β-catenin pathway in cervical cancer. |
