TERT Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 18994-1-AP

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Freight/Packing

Con: 17 μg/150 μl

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Tested Applications

Applications:
ELISA, WB
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Species specificity:
human

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
telomerase reverse transcriptase

Calculated molecular weight:
127 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TERT

Synonyms
EST2, hEST2, hTERT, TCS1, Telomerase catalytic subunit, TERT, TP2, TRT
Background

TERT,also named as EST2, TCS1 and TRT, belongs to the reverse transcriptase family and Telomerase subfamily. Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Activation of telomerase has been implicated in cell immortalization and cancer cell pathogenesis. TERT elongates telomeres by adding simple sequence repeats to chromosome ends. TERT can modulate Wnt signaling and plays important roles in aging and antiapoptosis. Mutation of TERT are associated with susceptibilty to aplastic anemia (AA), coronary artery disease (CAD), dyskeratosis congenita autosomal dominant (ADDKC) and idiopathic pulmonary fibrosis. Catalog#18994-1-AP is rabbit polyclonal antibody that can recognize all the 3 TERT isoforms.


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