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UPK2-Specific Polyclonal antibody

UPK2-Specific Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 19733-1-AP

Synonyms

UP2, UPII, upk 2, UPK2, UPK2-Specific, uroplakin 2, Uroplakin II

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human bladder tissue using UPK2-Specific Polyclonal antibody (19733-1-AP)

    IHC staining of human bladder using 19733-1-AP

    Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 19733-1-AP (UPK2-Specific Antibody) at dilution of 1:200 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human bladder tissue using UPK2-Specific Polyclonal antibody (19733-1-AP)

    IHC staining of human bladder using 19733-1-AP

    Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 19733-1-AP (UPK2-Specific Antibody) at dilution of 1:200 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human bladder tissue using UPK2-Specific Polyclonal antibody (19733-1-AP)

    IHC staining of human bladder using 19733-1-AP

    Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 19733-1-AP (UPK2-Specific Antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human bladder tissue using UPK2-Specific Polyclonal antibody (19733-1-AP)

    IHC staining of human bladder using 19733-1-AP

    Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 19733-1-AP (UPK2-Specific Antibody) at dilution of 1:50 (under 40x lens).

Tested Applications

Positive IHC detected inhuman bladder tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

19733-1-AP targets UPK2-Specific in IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name uroplakin 2
Calculated Molecular Weight 19 kDa
GenBank Accession NumberNM_006760
Gene Symbol UPK2
Gene ID (NCBI) 7379
RRIDAB_2878602
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention (PMID: 8175808). Uroplakin-2 (UPK2) is a single-pass type I membrane protein. UPK2 may play an important role in regulating the assembly of the AUM.

Protocols

Product Specific Protocols
IHC protocol for UPK2-Specific antibody 19733-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols