Vinculin Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 12744-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
vinculin

Calculated molecular weight:
1133aa,124 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
VCL

Synonyms
VCL, Metavinculin, MVCL, CMD1W, vinculin
Background

VCL belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. VCL is a cytoskeletal protein associated with cell-cell and cell-matrix junctions. VCL regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It plays an important role in cell morphology and locomotion.


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