p57Kip2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 23317-1-AP

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Con: 65 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Jurkat cells

Positive IHC detected in:
human placenta tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cyclin-dependent kinase inhibitor 1C (p57, Kip2)

Calculated molecular weight:
316aa,32 kDa

Observed molecular weight:
57 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CDKN1C

Synonyms
BWCR, BWS, CDKN1C, KIP2, p57, p57Kip2, WBS
Background

CDKN1C, also named as p57KIP2 and KIP2, belongs to the CDI family. CDKN1C is a potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. It is a negative regulator of cell proliferation. CDKN1C may play a role in maintenance of the non-proliferative state throughout life.


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