Product Information
18303-1-AP targets Angiotensin in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| Calculated Molecular Weight | 53 kDa |
| GenBank Accession Number | BC011519 |
| Gene Symbol | AGT |
| Gene ID (NCBI) | 183 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P01019 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Angiostatin is a part gene (34-43aa) of Angiotensinogen (Serpin A8, 485aa). In response to lowered blood pressure, the enzyme renin cleaves angiotensin-1 (34-43aa) from angiotensinogen. ACE (angiotensin converting enzyme) then removes a dipeptide to yield the physiologically active peptide angiotensin-2 (34-41aa), the most potent pressor substance known, which helps regulate volume and mineral balance of body fluids. Angiotensin-3 (35-41aa) stimulates aldosterone release.
