PR Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66300-1-Ig |CloneNo.: 3D1D12

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Freight/Packing

Con: 150 μg/150 μl

Choose size:

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Species specificity:
human

Positive IHC detected in:
human breast cancer tissue

Recommended dilution:
IHC : 1:1000-1:5000

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
progesterone receptor

Calculated molecular weight:
933aa,99 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PGR

Synonyms
NR3C3, PGR, PR, progesterone receptor
Background

PGR, also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.


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