CDC27; APC3 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 10918-1-AP

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Freight/Packing

Con: 58 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
K-562 cells, Jurkat cells

Positive IP detected in:
K-562 cells

Positive IHC detected in:
human prostate cancer tissue

Positive IF detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cell division cycle 27 homolog (S. cerevisiae)

Calculated molecular weight:
92 kDa

Observed molecular weight:
92 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CDC27

Synonyms
ANAPC3, APC3, CDC27, CDC27 homolog, CDC27Hs, D0S1430E, D17S978E, H NUC, HNUC
Background

CDC27/APC3 is a component of the anaphase-promoting complex (APC/cyclosome), which is composed of eight subunits and highly conserved in eukaryotic cells. The APC/cyclosome complex acts as a cell cycle-regulated E3 ubiquitin ligase which mediates ubiquitination and subsequent degradation of target proteins, and lead to the progression control through mitosis and the G1 phase of the cell cycle.


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