ECHS1 Antibody 14 Publications

Rabbit Polyclonal| Catalog number: 11305-1-AP

Featured Product KD/KO validated

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Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human liver tissue,HeLa cells, PC-3 cells, HepG2 cells, L02 cells, HT-1080 cells, mouse liver tissue, rat heart tissue

Positive IP detected in:
PC-3 cells

Positive IHC detected in:
human prostate cancer tissue, human liver tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2400
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:25-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial

Calculated molecular weight:
31 kDa

Observed molecular weight:
31 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ECHS1

Synonyms
ECHS1, ECoH-1, Enoyl CoA hydratase 1, SCEH
Background

Enoyl-coenzyme A hydratase (ECHS1) is a mitochondrial protein which catalyzes the hydration of 2-trans-enoyl-coenzyme A intermediates to L-3-hydroxyacyl-coenzyme A, playing key role in metabolism of fatty acids in mitochondria. ECHS1 is highly expressed in muscle, liver and fibroblasts. Altered expression of ECHS1 has been considered as a characteristic feature of mitochondria dysfunction. (23275097, 23235493)


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