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INSRR Polyclonal antibody

INSRR Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 55112-1-AP

Synonyms

INSRR, IR related receptor, IRR

Validation Data Gallery

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  • Western Blot (WB) analysis of mouse kidney tissue using INSRR Polyclonal antibody (55112-1-AP)

    WB analysis of mouse kidney using 55112-1-AP

    mouse kidney tissue were subjected to SDS PAGE followed by western blot with 55112-1-AP (INSRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

  • Western Blot (WB) analysis of human brain tissue using INSRR Polyclonal antibody (55112-1-AP)

    WB analysis of human brain using 55112-1-AP

    human brain tissue were subjected to SDS PAGE followed by western blot with 55112-1-AP (INSRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Tested Applications

Positive WB detected inmouse kidney tissue, human brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

55112-1-AP targets INSRR in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name IR related receptor
Calculated Molecular Weight 144 kDa
Observed Molecular Weight 150-155 kDa
GenBank Accession NumberNM_014215
Gene Symbol INSRR
Gene ID (NCBI) 3645
RRIDAB_10859077
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

INSRR, also named as IRR, belongs to the protein kinase superfamily, Tyr protein kinase family and INS receptor subfamily. It probably binds an INS related protein and has a tyrosine-protein kinase activity. It phosphorylates the INS receptor substrates IRS-1 and IRS-2. INSRR is a heterotetrameric transmembrane receptor composed of two alpha and two beta chains linked by disulfide bonds. INSRR shares high homology with the INS (IR) and the IGF-1R, but doesn't bind any of IR and IGF-1R known ligands. The antibody is specific to INSRR.

Protocols

Product Specific Protocols
WB protocol for INSRR antibody 55112-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols