PLG Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66399-1-Ig |CloneNo.: 1F6A11

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human plasma tissue

Positive IHC detected in:
human liver cancer tissue

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
plasminogen

Calculated molecular weight:
810aa,91 kDa

Observed molecular weight:
105 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PLG

Synonyms
Angiostatin, DKFZp779M0222, plasminogen, PLG
Background

Plasminogen is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Plasminogen is synthesized in the liver, and it circulates in the blood, with a half-life of 2.2 days. Plasminogen is the precursor of plasmin, which lyses fibrin clots to fibrin degradation products (FDP) and D-dimer; the conversion to active protease is mediated by tissue-type (tPA) and urokinase-type (uPA) plasminogen activators. Defects in plasminogen are likely a cause of thrombophilia and ligneous conjunctivitis.


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