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J Neurol Sci
Immunolocalization of Tom1 in relation to protein degradation systems in Alzheimer's disease.
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TOM1 is a member of VHS (VPS-27, Hrs, and STAM)-domain-containing protein family that functions as adaptor proteins in the intracellular trafficking and sorting of plasma membrane proteins. TOM1 colocalized with key proteins of the protein-degradation systems. Recently TOM1 has been reported to be localized in the hallmarks of AD pathology (27206884).