CD25 Monoklonaler Antikörper

CD25 Monoklonal Antikörper für FC

Wirt / Isotyp

Ratte / IgG1, lambda

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Atlantic Blue™ Fluorescent Dye

CloneNo.

PC61.5

Kat-Nr. : AB-65137

Synonyme

CD25, Il2r, Il2ra, Ly 43



Geprüfte Anwendungen

Erfolgreiche Detektion in FCplate-bound Anti-CD3 and Anti-CD28 stimulated mouse splenocytes

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

AB-65137 bindet in FC CD25 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Ratte / IgG1, lambda
Klonalität Monoklonal
Typ Antikörper
Immunogen k.A.
Vollständiger Name interleukin 2 receptor, alpha chain
GenBank-ZugangsnummerBC114437
Gene symbol Il2ra
Gene ID (NCBI) 16184
Konjugation Atlantic Blue™ Fluorescent Dye
Excitation/Emission maxima wavelengths404 nm / 458 nm
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer PBS with 0.09% sodium azide.
LagerungsbedingungenStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

Proliferation of T lymphocytes is triggered by the interaction of IL-2 with its specific receptor following T lymphocyte activation. The receptor for IL-2 has three forms, generated by different combinations of three different proteins, the alpha chain (IL-2R alpha), the beta chain (IL-2R beta), and the gamma chain (IL-2R gamma) (PMID: 8476561). IL-2R alpha (also known as CD25) is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. CD25 is also found on natural CD4+Foxp3+ Treg cells (PMID: 22585674).

Protokolle

Produktspezifische Protokolle
FC protocol for Atlantic Blue™ CD25 antibody AB-65137Protokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen