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MEF2C Monoklonaler Antikörper

MEF2C Monoklonal Antikörper für ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

ELISA

Konjugation

Unkonjugiert

CloneNo.

1F4B12

Kat-Nr. : 60124-1-Ig

Synonyme

Galerie der Validierungsdaten

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  • Western Blot (WB) analysis of SH-SY5Y cells using MEF2C Monoclonal antibody (60124-1-Ig)

    WB analysis of SH-SY5Y using 60124-1-Ig

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 60124-1-Ig (MEF2C antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

Geprüfte Anwendungen

Empfohlene Verdünnung

AnwendungVerdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

60124-1-Ig bindet in ELISA MEF2C und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen MEF2C fusion protein Ag0020
Vollständiger Name myocyte enhancer factor 2C
Berechnetes Molekulargewicht 51 kDa
GenBank-ZugangsnummerBC156603
Gene symbol MEF2C
Gene ID (NCBI) 4208
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Caprylsäure/Ammoniumsulfat-Präzipitation
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MEF2C belongs to the MEF2 family. It is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. It is crucial for normal neuronal development, distribution, and electrical activity in the neocortex and is necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. This protein is required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. It may also be involved in neurogenesis and in the development of cortical architecture. This antibody is a mouse monoclonal antibody raised against a peptide mapping within human MEF2C.

Read more about this antibody on the blog:http://blog.ptglab.com/index.php/mef2c-antibody-features-in-nature-biotechnology/