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SGK3 Polyklonaler Antikörper

SGK3 Polyklonal Antikörper für IHC,ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC,ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22100-1-AP

Synonyme

CISK, SGK3, SGKL

Galerie der Validierungsdaten

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  • Immunohistochemistry (IHC) staining of human liver cancer tissue using SGK3 Polyclonal antibody (22100-1-AP)

    IHC staining of human liver cancer using 22100-1-AP

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 22100-1-AP (SGK3 Antibody) at dilution of 1:200 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human liver cancer tissue using SGK3 Polyclonal antibody (22100-1-AP)

    IHC staining of human liver cancer using 22100-1-AP

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 22100-1-AP (SGK3 Antibody) at dilution of 1:200 (under 40x lens).

Geprüfte Anwendungen

Erfolgreiche Detektion in IHChumanes Leberkarzinomgewebe
Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

AnwendungVerdünnung
Immunhistochemie (IHC)IHC : 1:100-1:400
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

22100-1-AP bindet in IHC,ELISA SGK3 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SGK3 fusion protein Ag17308
Vollständiger Name serum/glucocorticoid regulated kinase family, member 3
Berechnetes Molekulargewicht 496 aa, 57 kDa
Beobachtetes Molekulargewicht 42 kDa, 57 kDa
GenBank-ZugangsnummerBC015326
Gene symbol SGK3
Gene ID (NCBI) 23678
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Serum- and glucocorticoid-inducible kinase 3 (SGK3) is a protein kinase of the AGC family of protein kinase A, protein kinase G, and protein kinase C and functions downstream of phosphatidylinositol 3-kinase (PI3K)(PMID:21084382). It is also named as DKFZp781N0293, CISK, SGK2, SGKL and may be involved in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. SGK3 mediates cell IL-3-dependent survival signals (PMID:12397388). SGK3 has 2 isoforms produced by alternative splicing with the molecular weight of 57 kDa and 53 kDa and there is a isoform X3 can be detected with 378 amino acids(Sequence ID: ref|XP_005251262.1|).