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Anticorps Monoclonal anti-MEF2C

MEF2C Monoclonal Antibody for ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

ELISA

Conjugaison

Non conjugué

CloneNo.

1F4B12

N° de cat : 60124-1-Ig

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of SH-SY5Y cells using MEF2C Monoclonal antibody (60124-1-Ig)

    WB analysis of SH-SY5Y using 60124-1-Ig

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 60124-1-Ig (MEF2C antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

Applications testées

Dilution recommandée

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

60124-1-Ig cible MEF2C dans les applications de ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgG1
Clonalité Monoclonal
Type Anticorps
Immunogène MEF2C Protéine recombinante Ag0020
Nom complet myocyte enhancer factor 2C
Masse moléculaire calculée 51 kDa
Numéro d’acquisition GenBankBC156603
Symbole du gène MEF2C
Identification du gène (NCBI) 4208
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Précipitation de l'acide caprylique/du sulfate d'ammonium
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

MEF2C belongs to the MEF2 family. It is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. It is crucial for normal neuronal development, distribution, and electrical activity in the neocortex and is necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. This protein is required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. It may also be involved in neurogenesis and in the development of cortical architecture. This antibody is a mouse monoclonal antibody raised against a peptide mapping within human MEF2C.

Read more about this antibody on the blog:http://blog.ptglab.com/index.php/mef2c-antibody-features-in-nature-biotechnology/