AADAT Polyklonaler Antikörper

AADAT Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13031-1-PBS

Synonyme

2 aminoadipate transaminase, 2-aminoadipate aminotransferase, 2-aminoadipate transaminase, Alpha-aminoadipate aminotransferase, aminoadipate aminotransferase

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  IHC staining of mouse cerebellum using 13031-1-AP (same clone as 13031-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 13031-1-AP (AADAT antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13031-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 13031-1-AP (same clone as 13031-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer using 13031-1-AP (AADAT antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13031-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 13031-1-AP (same clone as 13031-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer using 13031-1-AP (AADAT antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 13031-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

13031-1-PBS bindet in IHC, Indirect ELISA AADAT und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: AADAT fusion protein Ag3676
• Vollständiger Name: aminoadipate aminotransferase
• Berechnetes Molekulargewicht: 429 aa, 48 kDa
• GenBank-Zugangsnummer: BC031068
• Gene symbol: AADAT
• Gene ID (NCBI): 51166
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

AADAT (alpha-aminoadipate aminotransferase), also known as KAT (kynurenine aminotransferase) II, is a primary enzyme in the brain for catalysing the transamination of kynurenine to KYNA (kynurenic acid). KYNA is the only known endogenous antagonist of the N-methyl-D-aspartate receptor. AADAT is also involved in lysine metabolism by catalyzing the transamination of aminoadipate to a-ketoadipate (PMID: 17024659, 18056995). The human AADAT enzyme is also predicted to contain a mitochondrial cleavage signal, suggesting that AADAT is a mitochondrial protein (PMID: 19826765).