ABCA3 Polyklonaler Antikörper

ABCA3 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27450-1-PBS

Synonyme

150 Kda mature form, ABC C transporter, ABC3, ABCA 3, ABC-C transporter

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  WB analysis using 27450-1-AP (same clone as 27450-1-PBS)

  unboiled rat lung tissue were subjected to SDS PAGE followed by western blot with 27450-1-AP (ABCA3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27450-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 27450-1-AP (same clone as 27450-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 27450-1-AP (ABCA3 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27450-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 27450-1-AP (same clone as 27450-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 27450-1-AP (ABCA3 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27450-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 27450-1-AP (same clone as 27450-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 27450-1-AP (ABCA3 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27450-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

27450-1-PBS bindet in WB, IHC, Indirect ELISA ABCA3 und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ABCA3 fusion protein Ag24749
• Vollständiger Name: ATP-binding cassette, sub-family A (ABC1), member 3
• Beobachtetes Molekulargewicht: 140-160 kDa
• GenBank-Zugangsnummer: BC140895
• Gene symbol: ABCA3
• Gene ID (NCBI): 21
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ABCA3 belongs to the ATP-binding cassette (ABC) transporter superfamily. ABCA3, which is expressed in alveolar type II pneumocytes and localizes predominantly to the limiting membrane of lamellar bodies, is critical for synthesis of surfactant(PMID: 17267394). Mutation of the ABCA3 gene causes fatal surfactant deficiency in newborns(PMID: 15044640).