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ABCB10 Rekombinanter Antikörper

ABCB10 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251920E7

Kat-Nr. : 86853-1-PBS

Synonyme

ABC transporter 10 protein, ABC-me protein, ABC-mitochondrial erythroid protein, ATP-binding cassette sub-family B member 10, mitochondrial, ATP-binding cassette transporter 10

Filter:
  • Western Blot (WB) analysis of various lysates using ABCB10 Recombinant monoclonal antibody (86853-1-RR)

    WB analysis using 86853-1-RR (same clone as 86853-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86853-1-RR (ABCB10 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86853-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86853-1-PBS bindet in WB, Indirect ELISA ABCB10 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen ABCB10 fusion protein Ag6203
Vollständiger Name ATP-binding cassette, sub-family B (MDR/TAP), member 10
Berechnetes Molekulargewicht 79 kDa
Beobachtetes Molekulargewicht 60 kDa
GenBank-ZugangsnummerBC064930
Gene symbol ABCB10
Gene ID (NCBI) 23456
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ABCB10 (also known as ABC-me or M-ABC2) is an inner-mitochondrial-membrane ATP-binding cassette transporter that forms homodimers with its nucleotide-binding domain facing the matrix. ABCB10 is now recognized as a multifunctional protein that couples mitochondrial export activity to cellular antioxidant defence. During red-cell development it stabilises the iron importer mitoferrin-1 (Mfrn1), thereby sustaining heme synthesis, whereas in cardiac and other non-erythroid tissues it attenuates oxidative damage by limiting mitochondrial ROS accumulation. PMID: 22884976