ABCG8 Polyklonaler Antikörper

ABCG8 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24453-1-PBS

Synonyme

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  WB analysis using 24453-1-AP (same clone as 24453-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24453-1-AP (ABCG8 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24453-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

24453-1-PBS bindet in WB, Indirect ELISA ABCG8 und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ABCG8 fusion protein Ag19879
• Vollständiger Name: ATP-binding cassette, sub-family G (WHITE), member 8
• Berechnetes Molekulargewicht: 673 aa, 76 kDa
• Beobachtetes Molekulargewicht: 70 kDa
• GenBank-Zugangsnummer: BC113657
• Gene symbol: ABCG8
• Gene ID (NCBI): 64241
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ABCG8(ATP-binding cassette sub-family G member 8) and ABCG5(ATP-binding cassette protein G5) are members of the ABC transporter family and are half-type ABC transporters, which consist of six transmembrane helices and one nucleotide-binding domain. ABCG5 and ABCG8 form a heterodimer (ABCG5/ABCG8). Mutations in either ABCG5 or ABCG8 cause a genetic disorder, sitosterolemia. Patients with sitosterolemia show high plant sterol levels and develop hypercholesterolemia and atherosclerosis at a young age.(PMID: 36839356)