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ABR Rekombinanter Antikörper

ABR Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241121G1

Kat-Nr. : 84011-6-PBS

Synonyme

MDB, active BCR related gene, 241121G1

Filter:
  • Western Blot (WB) analysis of various lysates using ABR Recombinant antibody (84011-6-RR)

    WB analysis using 84011-6-RR (same clone as 84011-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84011-6-RR (ABR antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84011-6-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using ABR Recombinant antibody (84011-6-RR)

    WB analysis using 84011-6-RR (same clone as 84011-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84011-6-RR (ABR antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84011-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84011-6-RR

    Affinity and Kinetic Characterization of 84011-6-RR

    Biolayer interferometry (BLl) kinetic assays of 84011-6-RR against Human ABR were performed. The affinity constant is 4.96 nM.

Geprüfte Anwendungen

Produktinformation

84011-6-PBS bindet in WB, Indirect ELISA ABR und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen ABR fusion protein Ag29522
Vollständiger Name active BCR-related gene
Berechnetes Molekulargewicht 98 kDa
Beobachtetes Molekulargewicht97-100 kDa
GenBank-ZugangsnummerNM_021962
Gene symbol ABR
Gene ID (NCBI) 29
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ABR (Active breakpoint cluster region-related protein) is the only protein known in humans and mice to share high homology with BCR (68% amino acid identity). BCR(Breakpoint cluster region) gene was originally identified due to its involvement in a specific chromosomal translocation that causes the development of chronic myeloid leukemia and a subset of acute lymphoblastic leukemia. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. (PMID: 17116687, PMID: 37507586)