ACSL6 Polyklonaler Antikörper

ACSL6 Polyklonal Antikörper für WB, IHC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13847-1-PBS

Synonyme

ACSL 6, Arachidonate--CoA ligase, EC:6.2.1.15, EC:6.2.1.3, FACL6

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  WB analysis using 13847-1-AP (same clone as 13847-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13847-1-AP (ACSL6 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13847-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 13847-1-AP (same clone as 13847-1-PBS)

  IP result of anti-ACSL6 (IP:13847-1-AP, 4ug; Detection:13847-1-AP 1:2000) with mouse brain tissue lysate 2120 ug. This data was developed using the same antibody clone with 13847-1-PBS in a different storage buffer formulation.

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  IHC staining of human urothelial carcinoma using 13847-1-AP (same clone as 13847-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human urothelial carcinoma tissue slide using 13847-1-AP (ACSL6 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13847-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas cancer using 13847-1-AP (same clone as 13847-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 13847-1-AP (ACSL6 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13847-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

13847-1-PBS bindet in WB, IHC, IP, Indirect ELISA ACSL6 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ACSL6 fusion protein Ag4817
• Vollständiger Name: acyl-CoA synthetase long-chain family member 6
• Berechnetes Molekulargewicht: 78 kDa
• Beobachtetes Molekulargewicht: 74 kDa
• GenBank-Zugangsnummer: BC047453
• Gene symbol: ACSL6
• Gene ID (NCBI): 23305
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ACSL6 (Acyl-CoA Synthetase Long Chain Family Member 6) is a long-chain lipoyl-coenzyme A synthetase that is mainly responsible for catalyzing the binding of long-chain fatty acids to coenzyme A to form acyl-coenzyme A (Acyl-CoA). ACSL6 is involved in fatty acid metabolic transporter and the synthesis of cell membrane phospholipids, which affects the cell structure and function. ACSL6 plays an extremely important role in the pathogenesis of cancers such as hepatocellular carcinoma, lung cancer and neuroblastoma, suggesting that it may serve as a biomarker and therapeutic target for cancer therapy.