ACVR1B Polyklonaler Antikörper

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• KD/KO Validated

ACVR1B Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10086-1-PBS

Synonyme

activin A receptor, type IB, Activin receptor like kinase 4, Activin receptor type 1B, Activin receptor type-1B, Activin receptor-like kinase 4

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  WB analysis using 10086-1-AP (same clone as 10086-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 10086-1-AP (ACVR1B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10086-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 10086-1-AP (same clone as 10086-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 10086-1-AP (ACVR1B Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10086-1-PBS in a different storage buffer formulation.

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  WB analysis of HepG2 using 10086-1-AP (same clone as 10086-1-PBS)

  DMSO treated HepG2 cells were subjected to SDS PAGE followed by western blot with 10086-1-AP (ACVR1B Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10086-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

10086-1-PBS bindet in WB, Indirect ELISA ACVR1B und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ACVR1B fusion protein Ag0129
• Vollständiger Name: activin A receptor, type IB
• Berechnetes Molekulargewicht: 57 kDa
• Beobachtetes Molekulargewicht: 50 kDa
• GenBank-Zugangsnummer: BC000254
• Gene symbol: ACVR1B
• Gene ID (NCBI): 91
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ACVR1B (ALK4, activin A receptor type 1B) is a transforming growth factor-beta (TGF-beta) superfamily member (PMID: 37020544). A potential role for ACVR1B in regulating muscle mass is that it is part of the transforming growth factor b (TGFb) pathway regulating myostatin (PMID: 21063444).

{{ptg:RelatedPrimaryAntibodies}}