ADAM11 Polyklonaler Antikörper

ADAM11 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32970-1-PBS

Synonyme

ADAM 11, Disintegrin and metalloproteinase domain-containing protein 11, MDC, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein

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  WB analysis using 32970-1-AP (same clone as 32970-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32970-1-AP (ADAM11 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32970-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

32970-1-PBS bindet in WB, Indirect ELISA ADAM11 und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ADAM11 fusion protein Ag35877
• Vollständiger Name: ADAM metallopeptidase domain 11
• Berechnetes Molekulargewicht: 83kDa
• Beobachtetes Molekulargewicht: 83 kDa
• GenBank-Zugangsnummer: NM_001318933
• Gene symbol: ADAM11
• Gene ID (NCBI): 4185
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ADAM11 (A Disintegrin And Metalloprotease 11) is a non-catalytic, transmembrane member of the ADAM family. Although it retains the prototypical multi-domain architecture (signal peptide ‑ pro‑domain ‑ metalloprotease-like ‑ disintegrin ‑ cysteine-rich ‑ EGF-like ‑ TM ‑ cytoplasmic tail), it lacks the consensus HEXGHXXGXXHD zinc-binding motif, rendering it proteolytically inactive . Instead, ADAM11 functions as a cell-adhesion and signalling scaffold. (PMID: 31236626)