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ADAM15 Polyklonaler Antikörper

ADAM15 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27124-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using ADAM15 Polyclonal antibody (27124-1-AP)

    WB analysis using 27124-1-AP (same clone as 27124-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27124-1-AP (ADAM15 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27124-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27124-1-PBS bindet in WB, Indirect ELISA ADAM15 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ADAM15 fusion protein Ag25947
Vollständiger Name ADAM metallopeptidase domain 15
Berechnetes Molekulargewicht 93 kDa
Beobachtetes Molekulargewicht70 kDa
GenBank-ZugangsnummerBC014566
Gene symbol ADAM15
Gene ID (NCBI) 8751
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ADAM15, a member of the ADAM (a disintegrin and metalloprotease) family, is a membrane protein containing both protease and adhesion domains and may be involved in tumor invasion and metastasis (PMID:15756594). It is also named as MDC15. ADAM15 is required for the activation of the FAK and Src pathways to generate apoptosis resistance in response to apoptotic signalling or cell stress (PMID: 11741929). ADAM15 is processed during epididymal maturation and acrosome reaction and that it may play a role during sperm-egg binding. Jurkat and testicular cells expresses the precursor ADAM15 of 110 kDa, as well as the ADAM15 processing form, consisting of about 75-85 kDa (PMID:18390692). ADAM15 has some isoforms with the calculated molecular mass of 55~92 kDa.