ADAM23 Polyklonaler Antikörper

ADAM23 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32969-1-PBS

Synonyme

ADAM 23, Disintegrin and metalloproteinase domain-containing protein 23, MDC3, MDC-3, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3



Geprüfte Anwendungen

Produktinformation

32969-1-PBS bindet in WB, Indirect ELISA ADAM23 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ADAM23 fusion protein Ag35744
Vollständiger Name ADAM metallopeptidase domain 23
Berechnetes Molekulargewicht 832 aa, 92 kDa
Beobachtetes Molekulargewicht92 kDa, 70 kDa
GenBank-ZugangsnummerBC132765
Gene symbol ADAM23
Gene ID (NCBI) 8745
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ADAM23 (A disintegrin and metalloprotease protein 23), also known as MDC-3 (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) is a transmembrane type I glycoprotein involved with the development and maintenance of the nervous system, including neurite outgrowth, neuronal adhesion and differentiation and regulation of synaptic transmission. In addition, ADAM23 seems to participate in immune response and tumor establishment through interaction with different members of integrin receptors (PMID: 19692335). Two forms of ADAM23 have been previously described in primary cerebellar granule cells as an unprocessed precursor (100 kDa) and mature (70 kDa) protein, respectively (PMID: 29792904).