ADAM23 Polyklonaler Antikörper
ADAM23 Polyklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 32969-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
32969-1-PBS bindet in WB, Indirect ELISA ADAM23 und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | ADAM23 fusion protein Ag35744 |
| Vollständiger Name | ADAM metallopeptidase domain 23 |
| Berechnetes Molekulargewicht | 832 aa, 92 kDa |
| Beobachtetes Molekulargewicht | 92 kDa, 70 kDa |
| GenBank-Zugangsnummer | BC132765 |
| Gene symbol | ADAM23 |
| Gene ID (NCBI) | 8745 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
ADAM23 (A disintegrin and metalloprotease protein 23), also known as MDC-3 (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) is a transmembrane type I glycoprotein involved with the development and maintenance of the nervous system, including neurite outgrowth, neuronal adhesion and differentiation and regulation of synaptic transmission. In addition, ADAM23 seems to participate in immune response and tumor establishment through interaction with different members of integrin receptors (PMID: 19692335). Two forms of ADAM23 have been previously described in primary cerebellar granule cells as an unprocessed precursor (100 kDa) and mature (70 kDa) protein, respectively (PMID: 29792904).



