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ADAR1 Rekombinanter Antikörper

ADAR1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241595E8

Kat-Nr. : 85009-1-PBS

Synonyme

ADAR, DRADA, Double-stranded RNA-specific adenosine deaminase, adenosine deaminase RNA specific, 241595E8

Filter:
  • Western Blot (WB) analysis of various lysates using ADAR1 Recombinant antibody (85009-1-RR)

    WB analysis using 85009-1-RR (same clone as 85009-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85009-1-RR (ADAR1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85009-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85009-1-PBS bindet in WB, Indirect ELISA ADAR1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen ADAR1 fusion protein Ag5609
Vollständiger Name adenosine deaminase, RNA-specific
Berechnetes Molekulargewicht 136 kDa
Beobachtetes Molekulargewicht 110 kDa
GenBank-ZugangsnummerBC038227
Gene symbol ADAR1
Gene ID (NCBI) 103
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region(PMID:15556947). The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an IFN inducible ∼150 kDa protein and a constitutively expressed N-terminally truncated ∼110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters(PMID:11111054). It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria (DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities(PMID:17428802).