ADCY8 Polyklonaler Antikörper

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• KD/KO Validated

ADCY8 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus und mehr (1)

Anwendung

WB, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(5)

Kat-Nr. : 55065-1-AP

Synonyme

AC8, ADCY3, ADCY8, adenylate cyclase 8 (brain), Adenylate cyclase type 8, Adenylate cyclase type VIII, Adenylyl cyclase 8, ATP pyrophosphate lyase 8, HBAC1

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  WB analysis of Neuro-2a using 55065-1-AP

  Neuro-2a cells were subjected to SDS PAGE followed by western blot with 55065-1-AP (ADCY8 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis of Neuro-2a using 55065-1-AP

  Neuro-2a cells were subjected to SDS PAGE followed by western blot with 55065-1-AP (ADCY8 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis of SH-SY5Y using 55065-1-AP

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 55065-1-AP (ADCY8 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Neuro-2a-Zellen, SH-SY5Y-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 4 publications below
• IF: See 2 publications below

Produktinformation

55065-1-AP bindet in WB, IF, ELISA ADCY8 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: adenylate cyclase 8 (brain)
• Berechnetes Molekulargewicht: 140 kDa
• Beobachtetes Molekulargewicht: 140-150 kDa
• GenBank-Zugangsnummer: NM_001115
• Gene symbol: ADCY8
• Gene ID (NCBI): 114
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20℃ lagern. Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ADCY8 Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence. The antibody is specific to ADCY8.

Publikationen

Species	Application	Title
human	IF	Phytochemistry; Hypoglycemic flavonoids from Selaginella tamariscina (P.Beauv.) Spring.; Authors - Hong-Ping Long
human	WB	Function (Oxf); AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca2+ Channels.; Authors - Pulak Kar
human	WB	Nat Commun; A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction.; Authors - Xuexin Zhang ; KD Validated
rat	WB,IF	Mol Ther; Inhibition of adenylyl cyclase 8 prevents the upregulation of Orai1 channel which improves cardiac function after myocardial infarction; Authors - Débora Falcón
	WB	Int J Mol Sci; Combined Proteomic and Metabolomic Analysis Reveals Comprehensive Regulation of Somatostatin DNA Vaccine in Goats; Authors - Ge Qin