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Adiponectin Rekombinanter Antikörper

Adiponectin Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241082C6

Kat-Nr. : 83961-4-PBS

Synonyme

ADIPOQ, ADIPQTL1, Adipocyte, C1q and collagen domain-containing protein, Adipocyte complement-related 30 kDa protein, 30 kDa adipocyte complement-related protein

Filter:
  • Western Blot (WB) analysis of various lysates using Adiponectin Recombinant antibody (83961-4-RR)

    WB analysis using 83961-4-RR (same clone as 83961-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83961-4-RR (Adiponectin antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83961-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83961-4-RR

    Affinity and Kinetic Characterization of 83961-4-RR

    Biolayer interferometry (BLl) kinetic assays of 83961-4-RR against Human ADIPOQ were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

83961-4-PBS bindet in WB, Indirect ELISA Adiponectin und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Adiponectin fusion protein Ag16304
Vollständiger Name adiponectin, C1Q and collagen domain containing
Berechnetes Molekulargewicht 244 aa, 26 kDa
Beobachtetes Molekulargewicht29 kDa
GenBank-ZugangsnummerBC096308
Gene symbol Adiponectin
Gene ID (NCBI) 9370
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Adiponectin (AdipoQ), an adipocyte-derived hormone, is one of the most abundant adipokines in the blood circulation. Adiponectin modulates a number of metabolic processes, including improving INS sensitivity and anti-inflammatory activity. The role of AdipoQ in reproduction is not yet fully understood, but the expression of AdipoQ in reproductive tissues has been observed in various animals and humans, including chicken testis, bovine ovary, and human placenta. Adiponectin exerts its effects by activating a range of different signaling molecules via binding to two transmembrane AdipoQ receptors, AdipoR1 and AdipoR2. AdipoR1 is expressed primarily in the skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. AdipoQ May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors.